Trudy, an Idaho potato farmer, accidentally swallowed an organophosphate pesticide when her sprayer exploded. She thought that she would be alright because she didn’t immediately feel sick; but the next day she fell ill with the following symptoms: excessive salivation, frequent urination, and diarrhea. The doctors determined that the pesticide inhibited Trudy’s acteylcholinesterase activity.
1. What is the importance on this enzyme’s activity? Be detailed.
2. Since Ach is a major neurotransmitter of the parasympathetic system – detail the cranial nerves affected which manifested in Trudy’s symptoms.